Valeric acid

Research use only, not for human use.

Valeric acid or pentanoic acid is a straight chain alkyl carboxylic acid with the chemical formula CH3(CH2)3COOH.

Valeric acid or pentanoic acid is a straight chain alkyl carboxylic acid with the chemical formula CH3(CH2)3COOH. Like other low molecular weight carboxylic acids it has a very unpleasant odor. It is found naturally in the perennial flowering plant valerian (Valeriana officinalis) from which it gets its name.

Pentanoic acid, a short-chain fatty acid, is a product of bacterial metabolism and are associated with allergic skin disorders. Pentanoic acid (0-2 mM) strongly and dose-dependently induces thymic stromal lymphopoietin (TSLP) production in PAM212 cells. Pentanoic acid slightly induces the expression of Tnfa, Il1b and Il6 mRNA, but does not induce the protein levels of TNF-α expression. Pentanoic acid (2 mM) induced-TSLP production in keratinocytes is not related to FFAR2 and FFAR3, but mediated by activating ROCK signaling pathway, and is competetely inhibited by co-inhibition of Gq/11 and the ROCK signaling pathway.

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Pentanoic acid

Proteasome/Ubiquitin

Endogenous Metabolite

Human Endogenous Metabolite|ROCK

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109-52-4

102.13

C5H10O2

>98% (HPLC)

DMSO:10 mM;Water:20mg/mL(at 20°C)

CCCCC(O)=O

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(-20℃)

With Ice Pack

≥ 2 years